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KMID : 1134820110400111544
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Journal of the Korean Society of Food Science and Nutrition
2011 Volume.40 No. 11 p.1544 ~ p.1547
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Effect of Lotus (Nelumbo nucifera) Leaf Extract on Serum and Liver Lipid Levels of Rats Fed a High Fat Diet
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Lee Kyung-Seok
Lee Ki-Young
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Abstract
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Lotus (Nelumbo nucifera) leaf is known to be effective for "overcoming body heat" and stopping bleeding.It is commonly used as a traditional curing plant for the treatment of hematemesis, epistaxis, hemoptysis, hematuria, and metrorrhagia in traditional Chinese medicine. This study investigated on the effect of oral administration of lotus (Nelumbo nucifera) leaf extract on the serum and liver lipid levels of rats fed a high fat diet.Experimental rats were divided into five different experimental groups, including the general diet group (Cont), high fat diet with lotus leaf extract groups (HL40, HL80, HL120), and high fat diet group (HFG). Body weight significantly decreased in the HL120 sample compared to that of Cont. The weights of the livers and kidneys of rats corresponded to the increase in body weight. Total cholesterol and triglyceride contents in liver tissues of rats were lowest in the sample HL120 sample. The levels of total lipids,total cholesterol, and triglycerides in serum were lower in the HL120 sample compared to the HFG.
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KEYWORD
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lotus (Nelumbo nucifera) leaf, high fat diet, triglyceride, liver weights, rats
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